• A 5% decrease in BMI can slow down knee cartilage and meniscal degeneration.
• Higher BMI (>30 kg/m2) increases the risk of knee osteoarthritis.
• Weight loss is beneficial for pain relief and delaying joint deterioration.
• Exercise, such as a structured walking program, can improve pain and function in knee osteoarthritis.
• Topical NSAIDs can provide benefits similar to oral NSAIDs with fewer adverse effects.
• Repeated intra-articular glucocorticoid injections are not recommended for symptomatic knee osteoarthritis.
• Guidelines do not recommend certain therapies like massage therapy, manual therapy, and wedge insoles for knee osteoarthritis.

https://europepmc.org/article/MED/31238184

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